1 Complications will be recorded based on the type of therapy needed or action required to correct the complication as described in the Clavien-Dindo Classification and CTCAE v4.0.l
2,3,4 Recommeded to track via the EORTC Quality of Life Questionnaire - Core Questionnaire (EORTC QLQ-C30).
5 Includes bowel functioning, fecal leakage, stool frequency, diarrhea and dietary issues. Recommeded to track via the dietary subscale of the Memorial Sloan-Kettering Cancer Center (MSKCC) Bowel Function. Recommeded to track via the EORTC Quality of Life Questionnaire - Colorectal Cancer Module (EORTC QLQ-CR29).
6 Recommended to track via a single item from the EORTC Quality of Life Questionnaire - Liver Metastases Colorectal Module (EORTC QLQ-LMC21).
7 Recommended to track via the EORTC Quality of Life Questionnaire - Colorectal Cancer Module (EORTC QLQ-CR29).
8 Includes erectile dysfunction and vaginal symptoms. Recommended to track via the EORTC Quality of Life Questionnaire - Colorectal Cancer Module (EORTC QLQ-CR29).
9 Includes physical, emotional and social functioning and mobility and overall well-being. Recommended to track via the EORTC Quality of Life Questionnaire - Core Questionnaire (EORTC QLQ-C30).
10 Includes overall and cause-specific survival.
11 Includes pathologic complete response, margin status and recurrence and progression free survival.
12 Includes place of death and preference for place of death according to the patient.